Approved for For use in combination with fludarabine as a preparative regimen for allogeneic hematopoietic stem cell transplantation for AML and myelodysplastic syndrome. 12 CLINICAL PHARMACOLOGY 12.1 Mechanism of Action Treosulfan is an alkylating agent. DNA alkylation is thought to be responsible for the cytotoxic activities of treosulfan. Treosulfan showed… Side effects, costs, interactions,…
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