Approved for REDEMPLO is indicated as an adjunct to diet to reduce triglycerides in adults with familial chylomicronemia syndrome (FCS).. Plozasiran is a siRNA conjugated with GalNAc that degrades apoC-III mRNA through RNA interference, reducing triglycerides. Side effects, costs, interactions, manufacturer, and generic alternatives sourced from FDA labels, openFDA FAERS, and CMS NADAC pricing.
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