Approved for 1 INDICATIONS AND USAGE MACUGEN® (pegaptanib sodium injection) is indicated for the treatment of neovascular (wet) age-related macular degeneration. MACUGEN is indicated for the treatment of neovascular (wet) age-related macular degeneration ( 1 ).. 12.1 Mechanism of Action Pegaptanib is a selective vascular endothelial growth factor (VEGF) antagonist. VEGF is a secreted protein…
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