Approved for 1 INDICATIONS AND USAGE Estradiol gel, 0.1% is an estrogen indicated for the treatment of moderate to severe vasomotor symptoms due to menopause (1.1) . 1.1 Treatment of Moderate to Severe Vasomotor Symptoms due to Menopause. 12.1 Mechanism of Action Endogenous estrogens are largely responsible for the development and maintenance of the female reproductive system and secondary…
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