Approved for Acute ischemic stroke, Acute myocardial infarction, Acute massive pulmonary embolism. Binds to fibrin in a thrombus and converts entrapped plasminogen to plasmin, initiating local fibrinolysis with limited systemic proteolysis. Side effects, costs, interactions, manufacturer, and generic alternatives sourced from FDA labels, openFDA FAERS, and CMS NADAC pricing.
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